List of projects that received NCN funding
1. Rutenowe metalodendrymery jako nanoplatformy do terapii ferroptotycznej celowanej w GPX4/FSP1 w nowotworach lekoopornych [Ruthenium metalodendrimers as nanoplatforms for GPX4/FSP1-targeted ferroptotic therapy in drug-resistant cancers]
(Project leader: dr hab. Sylwia Michlewska, Laboratory of Microscopic Imaging and Specialized Biological Techniques)
Funding: 4 605 985,00 PLN (Competition: OPUS 30)
- PROJECT DESCRIPTION: The aim of the project is to develop an innovative nanoplatform based on ruthenium metalodendrimers, capable of simultaneously delivering siRNA silencing GPX4 and FSP1 together with doxorubicin (DOX), a chemotherapeutic drug.
2. Prognozowanie wp艂ywu ekologicznego gatunk贸w inwazyjnych w warunkach zmiany klimatu [Forecasting the ecological impact of invasive species under climate change conditions] (Project leader: dr hab. Ali Serhan Tarkan, Department of Ecology and Vertebrate Zoology) Funding: 1 439 500,00 PLN (Competition: OPUS 30)
- PROJECT DESCRIPTION: The project investigates how climate warming affects the ecological impact of two widespread fish species: the invasive round goby (Neogobius melanostomus) and the European perch (Perca fluviatilis), which is also expanding its range in response to environmental changes.
3. Mezozoiczna Rewolucja Jeziorna i najwi臋ksze wyzwanie ewolucyjne dla j臋tek (Ephemeroptera) [MesoRev] [Mesozoic Lacustrine Revolution and the greatest evolutionary challenge for mayflies (Ephemeroptera)] (Project leader: dr hab. Roman Hodunko, Department of Invertebrate Zoology and Hydrobiology) Funding: 1 146 920,00 PLN (Competition: OPUS 30)
- PROJECT DESCRIPTION: The project addresses a series of questions, which will be explored through the study of exceptionally well-preserved mayflies from the Triassic, as well as Jurassic and Cretaceous sites, where both Mesozoic and modern Cenozoic taxa occur. Key questions include: How did mayfly communities change from the Triassic to the Cretaceous? What morphological changes accompanied larvae as they shifted from standing waters to rivers and streams during the MLR? What are the qualitative and quantitative differences between pioneer mayfly assemblages in freshwater and modern ones? Will the use of modern technologies (3D scanning) enable accurate reconstruction of pioneer taxa inhabiting flowing waters? How will our understanding of the diversity and structure of Mesozoic mayfly taxocenoses change in light of results obtained using advanced imaging methods and statistical analyses?
4. Jak zmienno艣膰 wewn膮trzgatunkowa sprzyja inwazji [How intraspecific variability promotes invasion] (Project leader: Dr Dagmara B艂o艅ska, Institute of Ecology and Environmental Protection) Funding: 1 659 100,00 PLN (Competition: SONATA 21)
- PROJECT DESCRIPTION: The project focuses on the monkey goby (Neogobius fluviatilis) in two Polish rivers 鈥� the Bzura and the Pilica. These rivers are locations where the species has emerged in recent decades and is successfully spreading, making them ideal for observing its behaviour and environmental impact. The research aims to determine how the monkey goby spreads and utilises these rivers, how it interacts with other species, and what effect it has on the overall condition of the ecosystem.
5. Czy s艂odkowodne ma艂偶e przetrwaj膮 w antropogenicznie zmieniaj膮cym si臋 艣wiecie? [Will freshwater mussels survive in an anthropogenically changing world?] (Project leader: Dr Dariusz Krzysztof Halabowski, Department of Ecology and Vertebrate Zoology)
Funding: 2 880 970,00 PLN (Competition: SONATA 21)
- PROJECT DESCRIPTION: The aim of the project is to answer a seemingly simple question: which freshwater mussels have a chance of surviving in a rapidly changing world, and which are particularly vulnerable? To address this, the study uses a complex but well-described network of dependencies between mussels, fish and crayfish. A key role is played by the bidirectional relationship between bitterling fish and mussels: bitterlings deposit their eggs into the gill cavities of mussels, using them as 鈥渋ncubators鈥�, while the mussels themselves (only the Unionidae family) produce larvae parasitic on fish gills and fins. This system is further complicated by the presence of native and invasive species of mussels, fish and crayfish, as well as changing environmental conditions.
6. Filogeneza i ekologia takson贸w z rodziny Bacillariaceae z antropogenicznych ekosystem贸w wodnych [Phylogeny and ecology of taxa from the Bacillariaceae family in anthropogenic aquatic ecosystems] (Project leader: Dr Rafa艂 Olszy艅ski, Department of Algology and Mycology) Funding: 45 100,00 PLN (Competition: MINIATURA 10)
7. Metodologiczna optymalizacja multipleksowego protoko艂u barwienia immunofluorescencyjnego do kompleksowej analizy mikrogleju w sensorycznych narz膮dach oko艂okomorowych w szczurzym modelu wagotomii podprzeponowej [Methodological optimisation of a multiplex immunofluorescence staining protocol for comprehensive analysis of microglia in sensory circumventricular organs in a rat model of subdiaphragmatic vagotomy] (Project leader: Dr Anna Kobrzycka, Institute of Experimental Biology) Funding: 49 995,00 PLN (Competition: MINIATURA 10)
Edit and graphics: Mateusz Kowalski (Promotion Centre, Faculty of Biology and Environmental Protection, 91桃色)
Source: Kinga Mr贸wczy艅ska-Rybak (Project Office, Faculty of Biology and Environmental Protection, 91桃色)